Volume 8 Issue 12 (December, 2020)

Original Articles

Factors affecting success rates of IVF
Dr. Osho, Dr. Bharti Maheshwari

Background: Infertility is caused by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse. If the success rate predicted was found to be low then the candidate’s couple can take a conclusive decision such as not to go with the IVF cycle. The purpose of this study was to determine various factors affecting success rates and outcome. Materials and method: This clinical study entitled was carried out to assess the factors affecting success rates of IVF in the Department of Obstetrics and gynaecology, Muzaffarnagar Medical College, Muzaffarnagar. The total sample size was determined to be 100 subjects. Follicular growth was monitored by measurements of serum oestradiol and progesterone and by performing transvaginal sonography. Delivery rates were calculated according to cycle characteristics, including the number of oocytes retrieved, the number of transferred embryos and whether or not there had been the option of choosing embryos for transfer. Results: The mean age of the study population was 33.05±4.07 years with a age range of 26-40 years. The successful pregnancies (delivery rate %) was 30.0% among 26-30 years age group, 39.0% among 31-35 years age group and 31.0% among 36-40 years age group. The Fertilization rate (2 PN/oocytes exposed to sperm) was 66.0%. The Successful implantation rate was 27.0%. Majority (42.0%) reported that the main reason for infertility was male factor followed by mechanical (20.0%), Anovulation (23.0%) and Unknown among 15.0% subjects. Conclusion: Age at the time of IVF and FSH serum levels are the crucial factors to get success in assisted reproductive technology and frozen embryo transfer (FET) techniques, and should be considered. Keywords: Assisted reproductive technology, Frozen embryo transfer, Infertility, IVF

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