Journal of AdvancedMedical and Dental Sciences Research

Background: Dengue is one of the most prevalent mosquito-borne arboviral infection in India. It is characterized by leucopenia followed by thrombocytopenia. In general, dengue is a self-limiting acute febrile illness followed by a phase of critical defervescence, in which patients may improve or progress to a severe form. Severe illness is characterized by hemodynamic disturbances, increased vascular permeability, hypovolemia, hypotension, and shock. Materials and methods: Data were collected from patients attending outpatient and inpatient services in a hospital in North India. Total 58 patients of both sexes with age 35±10 years admitted with fever and found to have thrombocytopenia are included in the study. Data were collected after obtaining consent in due format. Data are collected by using interview, physical examination, sputum examination, and laboratory findings. Result: Out of 116 cases with severe thrombocytopenia, complications were present in 72 cases. Thirty eight patients had haemorrhagic dengue fever, 10 suffer from severe dehydration, 6 from DHF with bleeding manifestation, 6 from dengue shock syndrome, 4 from fever induced seizures, 8 from neurological complications. Conclusion: It one of the most common vector-borne diseases worldwide. thrombocytopenia can be used as predictor of complications in a patient with dengue fever. So both Clinical as well as laboratory monitoring of Dengue patients for hemorrhagic manifestations and marked thrombocytopenia is strongly recommended. Key words: Dengue, thrombocytopenia, Fever, Platelet count, Dengue Shock syndrome (DSS).