Bone grafting has become an integral part of Implant dentistry. Grafts are used in patients with inadequate bone volume or height which often requires the use of biomaterials during the surgical procedures to ensure implant success. Bony defects both horizontal and vertical defects that can be treated using graft materials, especially in the field of implant dentistry. Commonly used graft material includes autografts, allografts, xenografts, and alloplast. These materials mostly function as osteogenic, osteoconductive, osteoinductive scaffolds. Defects with four walls of host bone can be repaired with alloplasts alone or allografts. The loss of three or more bony walls mandates the addition of autogenous bone to the graft or the use of a membrane. The larger the defect, the more autogenous bone is required. Along with grafts to enhance healing membranes can be used, one of the recent advances of new generation platelet concentrate called PRF, which promotes bone regeneration, soft tissue healing, and better osseointegration can be achieved. All these biomaterials play a pivotal role in Regenerative dentistry, this article explains the various indications of bone substitutes and their specific applications in implant dentistry.
Key words: Biomaterial, Bone defects, Grafts, Implants, Platelet Rich Fibrin.