Background: Local anesthetics vary in their potency, allowing for concentrations that range typically from 0.5 to 4%. With advent of time and research, a variety of local anaesthetic solutions are used in dentistry. Hence; the present study was undertaken for assessing and comparing the local anaesthetic solution with two different concentration of adrenaline in patients undergoing dental extraction procedures. Materials & methods: A total of 50 patients scheduled to undergo extraction of mandibular first molar were enrolled in the present study. All the patients were broadly divided into two study groups as follows: Group 1: Patients receiving local anaesthesia (lignocaine) with 1:80000 concentrations of adrenaline, and Group 2: Patients receiving local anaesthesia (lignocaine) with 1:200000 concentration of adrenaline. Local anaesthesia was administered according to respective groups and various hemodynamic parameters were recorded. The assessment of analgesia was done by the clinical and recorded as 'successful', 'partial success', and 'failure'. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Results: While comparing the mean pulse rate at different time intervals, it was seen group 2 patients were associated with significantly higher alteration in the mean pulse rate at different time intervals. Also, it was seen that in comparison to group 1, group 2 patients were associated with significantly higher alteration in both systolic and diastolic blood pressure at different time intervals. Conclusion: The adrenaline at both the concentrations produced equal anaesthesia, adrenaline with concentration of 1:200000 showed significantly higher rise in hemodynamic parameters.
Key words: Adrenaline, Dental extraction, Local anaesthesia