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Volume 8 Issue 2 (February, 2020)
Review Articles
Toxicity Profile of Methotrexate in Patients on Treatment for Rheumatoid Arthritis- A Review | |
Md Miftah ur Rahman, Sheikh javeed Ahmad, Suhail Shariff, Rahul Vinay Chandra Tiwari, Sunil kumar, Bharti Wasan, Heena Tiwari | |
Methotrexate (MTX) is the cornerstone of treatment in rheumatoid arthritis (RA). It has already been used for over 40 years as an anchor treatment in a number of rheumatic diseases, thereby; it remains a gold standard of therapy for RA. The weekly low dose MTX provides a cost effective, efficacious and generally well tolerated treatment for RA. The physicians should be aware of the risks associated with MTX use and must monitor accordingly. The present review provides a concise discussion of the toxicity and safety of methotrexate in treatment of rheumatoid arthritis. Key words: Rheumatoid arthritis, MTX toxicity, MTX treatment. |
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