Background: Migraine is one of the most common causes of headaches in children and adolescents. The present study was conducted to compare sodium valproate vs propanalol in migraine. Materials & Methods: This study was conducted on 120 patients of migraine of both genders. Patients were divided into 2 groups. Group I patients were treated with propranolol, while patients in group II received sodium valproate. Results: Out of 120 patients, group I had males were 24 and females were 26. In group II, males were 28 and females were 22. Excellent result drug efficacy was seen in 32 in group I and 17 in group II, good in 15 in group I and 17 in group II, fair 7 in group I and 14 in group II and poor 6 in group I and 12 in group II. The difference was significant (P< 0.05). Conclusion: Authors found that propranolol is more effective in migraine as compared to sodium valproate.
Key words: Migraine, Propranolol, Sodium valproate