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Volume 7 Issue 11 (November, 2019)

Original Articles

Ulcerated hemangioma- Clinical characteristics, Microbiology and Response to adjunct antimicrobial therapy in children
Shipra Galhotra, Ashish Chhabra, Shaveta Kataria, Trimaan Kaur Bains

Background: Hemangiomas are considered to be the most common congenital anomalies in the children. Though asymptomatic in most of the children, these vascular lesions can present with ulceration and superimposed bacterial or fungal infection and if left untreated the ulceration can further complicate by hemorrhage, scarring and disfigurement. Although there are various options for the treatment, no single option is found to be universally effective. The study aimed at studying the microbiological profile of the ulcerated hemangiomas and role of adjunct appropriate antibiotics as per the culture-sensitivity report. Material and methods: 50 children suffering from ulcerated hemangiomas were included as case group patients. Control group consisted of age matched 50 children from the available existing data. Nature of the lesions and superimposed ulcers were studied in detail. Case group patients underwent inoculation of the swab taken from the ulcerated region. Antibiotics were prescribed according to the culture-sensitivity report in addition to the definite medical management. Clinical response in the form healing of the ulceration and hemangioma was studied by following a strict follow up protocol. Results: Methicillin Resistant Staphylococcus Aureus (MRSA) was found to be the most common organism in the swab inoculation. Candida albicans growth was seen in 4 patients. The mean time of ulcer healing was 11.36±3.66 days in control group as opposed to statistically significant much lesser mean time in the case group i.e. 6.78±2.01 days (p value- 0.000). The hemangioma lesions too responded better when clinical response was studied. There were 24 non-responders in the control group in comparison to 10 children in the case group and good response was seen in three times patients in the case group (p value- 0.002). Conclusion: Our study demonstrated the all ulcerated hemangiomas should undergo microbiological profile and the appropriate antibiotics need to be added other than the definite medical management while treating these lesions. Key words: Ulcerated hemangioma; Microbiological profile; Anti-microbiological agents; Clinical response

 
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