Background: The introduction of safe drugs enhanced the popularity of spinal anaesthesia. The present study was conducted to compare haemodynamical changes associated with different doses of ropivacaine in lower limb surgery. Materials & Methods: The present study was conducted on 84 patients of American Society of Anesthesiologists (ASA) physical status I and II of age group 20 - 65 years of both genders. Patients were divided into 2 groups of 42 patients each. Group I (42 patients) received 22.5 mg (3 mL) of 0.75% isobaric ropivacaine hydrochloride and group II (42 patients) received 15 mg (3 mL) of 0.5% isobaric ropivacaine hydrochloride. Mean pulse rate, respiratory rate, systolic and diastolic blood pressure was compared in both groups. Results: The mean pulse rate, SBP, DBP, respiratory rate recorded in both groups pre-operatively, at 0 min, 5, 10,20,40,60,75,90,120,150 and 180 minutes found to be non- significant (P> 0.05). Hypotension was present in 5 in group I and 6 in group II, bradycardia in 4 in group I and 5 in group II, headache in 3 in group I and 2 in group II and nausea in 6 in group I and 5 in group II. The difference was significant (P> 0.05). Conclusion: Both ropivacaine 0.75% and 0.5% equal in providing anesthesia with minimal side effects and thus recommended for lower limb surgeries.
Key words: Ropivacaine, Respiratory rate, Systolic blood pressure