Journal of AdvancedMedical and Dental Sciences Research

Background: It was shown that serum uric acid level was changed in more severe sepsis patients. The present study was conducted to evaluate level of uric acid in sepsis patients. Materials & Methods: The present study was conducted on 137 patients of sepsis of both genders. Sepsis was defined based on the Society of Critical Care Medicine, Surviving Sepsis Campaign 2012 definition. Patients underwent uric acid, basic metabolic profile, complete blood count, lactic acid, phosphorus, albumin and arterial blood gas assessment. We assessed hyperurecemia in patients presenting with sepsis and the morbidity rate. Results: Out of 137 patients, males were 71 and females were 66. 36 patients of diabetes had high uric acid, 16 had CAD, 21 had CVA, 10 had CHF and 7 had pulmonary disease. 28 had BMI >30, 23 had between 25-29.9 and 39 had 18.5- 24.9. The difference was significant (P<0.05). Out of 137 patients, 102 patients died and out of which 87 had high uric acid level. The difference between survived and died patients was significant (P< 0.05).Conclusion: Authors found that hyperurecemia was a predictor of sepsis in patients. Key words: Critical Care Medicine, hyperurecemia, sepsis.