Journal of AdvancedMedical and Dental Sciences Research

Background: Indians have the lowest high-density lipoprotein-cholesterol (HDL-C) and recent studies have revealed that a low HDL-C and high TC/HDL ratio is one of the major predictor for CAD. The present study was conducted to evaluate the effect of statins on glycemic control. Materials & Methods: The present study was conducted on 84 cases on statins of both genders. Patients above 30 years of age and on statins for at least 1 year with a fasting blood glucose level <100 mg/dl at the time of initiation of statin were included in the study. In all patients, lipid profile and side effects of statins was recorded. Results: Out of 84 patients, males were 52 and females were 32. Hypertension was present in 80, hypercholesterolemia in 82 and ischemic heart disease (IHD) in 39. The mean triglycerides in patients was 138.2 mg/dl, LDL was 124.8 mg/dl and HDL was 34.5 mg/dl. Headache was seen in 31, myalgia in 45, tingling in 28, loss of apetite in 45 and hepatitis in 14. The difference was non- significant (P> 0.05). Conclusion: Statins have a mild‑to‑moderate risk of developing DM. The dose of statins is an important factor that increases the risk of diabetes. Key words: Diabetes, Statins, LDL