Background: Oral submucous fibrosis (OSMF) is a well recognized potentially malignant condition of the oral cavity. Various factors have been implicated in the pathogenesis but there is strong evidence associating the disease with the habit of areca nut. There are very few reports to correlate the clinical stage to histopathological grading in OSMF. Aim: To correlate the clinical staging with histopathological grading in OSMF patients. Materials and Methods: The study was carried out on 40 patients of oral submucous fibrosis in the age range of 18 to 60 years. A detailed history of each patient was recorded along with clinical examination. Punch biopsy was performed for histopathological correlation. Clinical staging of the disease in terms of the ability to open one’s mouth was correlated with histopathological grading. Results: Out of 40 patients of oral submucous fibrosis, 5(12.5%) had histopathogic grade I, 27(67.5%) had histopathogic grade II and 8(20%) had histopathogic grade III. From them 33 patients of clinical grade II, 5(15.15%) had histopathogic grade I, 24(72.72%) had histopathogic grade II and 4(12.12%) had histopathogic grade III. Out of 7 patients of clinical grade III, none had histopathogic grade I, 3(42.86%) had histopathogic grade II and 4(57.14%) had histopathogic grade III. Conclusion: The correlation of clinical grade with histopathological grade of oral submucous fibrosis was significant (P=0.02).
Key Words: Oral submucous fibrosis, areca nut, clinical staging, histopathological grading
Received: 15 July, 2019 Revised: 19 August 2019 Accepted: 25 August 2019
Corresponding Author: Dr. Denil A. Solanki, M.D.S.(Oral Surgery), Assistant Professor, Department of Dentistry, P.D.U. Govt. Medical College, Rajkot
This article may be cited as: Rupapara RK, Solanki DA, Chawda J, Chavda RM. Oral Submucous Fibrosis: A clinico-histopathological comparative study in Gujarat. J Adv Med Dent Scie Res 2019;7(9):32-35.