Background: Gingival crevicular fluid (GCF) is a physiological fluid as well as an inflammatory exudate originating from the gingival plexus of blood vessels. The present study was conducted to compare GCF IL- 34 level in healthy, chronic periodontitis and aggressive periodontitis patients. Materials & Methods: The present study was conducted on 40 subjects with diagnosed cases of chronic and aggressive Periodontitis of both genders. 20 healthy subjects were taken as control. Plaque index, gingival index, probing depth and bleeding on probing were assessed for all the patients. The GCF samples from deepest probing depth were collected for IL-34 assessment. Detection of IL-34 levels was done by using Enzyme Linked Immuno-sorbent Assay.
Results: The mean PD in group I was 4.36, in group II was 6.37 and in group III was 1.28. The difference was significant (P< 0.05). The mean CAL in group I was 4.52, in group II was 6.48 and in group III was 0. The mean GI in group I was 1.98, in group II was 2.5 and in group III was 0.4. The difference was significant (P< 0.05). The mean GCF IL_ 34 level in group I was 104.5, in group II was 185.2 and in group III was 48.3. The difference was significant (P< 0.05). Conclusion: IL- 34 level in chronic periodontitis and aggressive periodontitis patients was significantly higher as compared to healthy subjects.
Key words: Aggressive periodontitis, Chronic periodontitis, IL- 34.
Received: 13 March, 2019 Revised: 02 August 2019 Accepted: 04 August 2019
Corresponding author: Dr. Surinder Sachdeva, Professor & HOD, Department of Periodontics, M.M College of Dental Sciences &Research, Maharishi Markandeshwar (Deemed to be University), Mullana Ambala, Haryana, India
This article may be cited as: Kochar D, Sachdeva S, Kaur A, Vakil N, Kamra M, Chhabra S. Evaluation of GCF in Healthy, Chronic Periodontitis and Aggressive Periodontitis Patients. J Adv Med Dent Scie Res 2019;7(8): 55-58.