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Volume 7 Issue 2 (February, 2019)

Original Articles

A comparative study to evaluate Efficacy of levofloxacin and moxifloxacin on outcome of multidrug-resistant tuberculosis treatment
Jitendra Kumar

Background: Although several studies have compared levofloxacin with other FQNs, such as ciprofloxacin or ofloxacin, studies comparing levofloxacin and moxifloxacin are lacking. So, Present study aimed to evaluate Efficacy of levofloxacin and moxifloxacin on outcome of multidrug-resistant tuberculosis treatment. Materials & methods: A total of 100 patients with MDR-TB were included in the present study. All the patients were broadly divided into two study groups with 50 patients in each group. Group A comprised of patients who were given levofloxacin as a part of treatment therapy, and Group B included patients who were given moxifloxacin as a part of treatment therapy. Treatment outcome was assessed in terms of success of treatment and presence and incidence of adverse effects. All the results were summarized in SPSS software. Results: Non-significant results were obtained while comparing the treatment outcome and associated adverse drug effects in between both the study groups.  Conclusion: Both the drugs can be used with equal efficacy in MDR-TB patients.
Key words: Levofloxacin, Moxifloxacin.
                                    
Received: 15 November  2018                                 Revised: 27 December 2018                          Accepted: 28 December 2018
Corresponding author: Dr. Jitendra Kumar, Associate Professor Department of T.B. & Chest, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India

This article may be cited as: Kumar J. A comparative study to evaluate Efficacy of levofloxacin and moxifloxacin on outcome of multidrug-resistant tuberculosis treatment. J Adv Med Dent Scie Res 2019;7(2): 151-153.

 
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