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Volume 7 Issue 7 (July, 2019)

Original Articles

Associations, Eosinophils and Serum IgE levels in Atopic dermatitis patients
Navtej Singh, Vinay Gera

Background: Atopic dermatitis (AD) is a chronic, non-contagious inflammatory skin disease. The present study was conducted to determine associations/sensitization, eosinophilia and IgE levels in Atopic dermatitis patients. Materials & Methods: The present study was conducted on 104 patients of Atopic dermatitis (AD) of both genders. The severity of AD was evaluated according to the SCORAD index. Eosinophils were measured in the differential white cell count by means of standard microscopic cytology. Sensitization studies were carried out and Total Serum IgE levels measured. Results: Out of 104 patients, males were 64 and females were 40. Manifestations among atopic dermatitis patients were asthma bronchiale (AB) seen in 55, allergic rhinitis (RC) in 46, sensitization to mites in 37, sensitization to bird feather in 23, sensitization to dust in 17 and sensitization to grass in 25. 52 males and 31 females showed peripheral blood eosinophilia of >6% of TLC.  Elevated total IgE levels (≥250 IU/ml) were seen in 53 males and 36 females while a positive family history of atopy was present in 35 males and 22 females. Conclusion: Common manifestations such as asthma bronchiale and allergic rhinitis were seen among atopic dermatitis patients. Most of the patients had peripheral blood eosinophilia and higher IgE levels.
Key words: Asthma bronchiale, Atopic dermatitis, Allergic rhinitis.

Received: 12 April, 2019                            Revised:  25 June 2019                             Accepted: 26 June 2019

Corresponding author: Col (Dr) Vinay Gera, Department of Dermatology Base Hospital Lucknow, U.P., India

This article may be cited as: Singh N, Gera V. Associations, Eosinophils and Serum IgE levels in Atopic dermatitis patients. J Adv Med Dent Scie Res 2019;7(7): 44-46.

 
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