The purpose of this study was to study the characteristics of indicators of the hemostasis system in patients with chronic inflammatory periodontal disease associated with metabolic syndrome. 70 patients of both sexes (43 women and 27 men) aged from 30 to 58 years old were examined. They were diagnosed with MS for the first time by an endocrinologist at the Clinic TGSI. The main group included patients -27 people with moderately severe CGP, 20 patients with CGP combined with MSIMT>25 kg/m2, and 23 patients with CGP combined with MS BMI> 25 kg/m2. The control data used the survey of 20 healthy people. It was revealed that the course of CGP with its combination with persons with a high body mass index is complicated by not only dysfunction of vascular endothelial cells, but also by increased consumption of hemocoagulation system factors and the risk of thrombohemorrhages. In response to the conditions created in the plasma link of the hemostasis system, the organism adaptively activates the platelet (cellular) link of the hemostasis system, thereby increasing the aggregation activity of the platelets. It is proved that the revealed violations in the hemostasis system must be considered when taking therapeutic measures in dental practice.
Key words: hemostasis; periodontitis; metabolic syndrome; atherogenic coefficient; hepatitis C.
Received: 8 February, 2019 Revised: 27 March, 2019 Accepted: 28 March, 2019
Corresponding Author: Dr. Jakhongir Abduvakilov, Department of Advanced Training in the Field of Orthopedic Dentistry, Tashkent State Dental Institute, Tashkent, Uzbekistan
This article may be cited as: Abduvakilov J, Rizaev J. Characteristic Features of Hemostasis System Indicators in Patients with Inflammatory Periodontal Diseases Associated with Metabolic Syndrome. J Adv Med Dent Scie Res 2019;7(4): 13-15.