Journal of AdvancedMedical and Dental Sciences Research

The oral cavity appears as an open ecosystem, with a dynamic balance between the entrances of microorganisms, colonization modalities, and host defenses aimed to their removal. Gingival and Periodontal diseases represent a major concern both in dentistry and medicine. The oral biofilm formation and development, and the inside selection of specific microorganisms have been correlated with the most common oral pathologies, such as dental caries, periodontal disease, and peri-implantitis. The mechanical removal of the biofilm and adjunctive use of antibiotic disinfectants or various antibiotics have been the conventional methods for periodontal therapy. Ozone (O3) is a triatomic molecule, consisting of three oxygen atoms, and its application in medicine and dentistry has been indicated for the treatment of 260 different pathologies. The beneficial biological effects of ozone, its anti-microbial activity, oxidation of bio-molecules precursors and microbial toxins implicated in periodontal diseases and its healing and tissue regeneration properties, make the use of ozone well indicated in all stages of gingival and periodontal diseases. The aim of this review article is to throw a light on the various aspects of basics of ozone therapy and discuss its application in the management of periodontal diseases.
Key words: Gingivitis; ozone therapy; periodontitis.