Journal of AdvancedMedical and Dental Sciences Research

Background: Oral lichen planus (OLP), the mucosal counterpart of cutaneous lichen planus, presents frequently in the fourth decade of life. Corticosteroids have been the mainstay of management of OLP; yet, other modalities like calcineurin inhibitors, retinoids, dapsone, hydroxychloroquine, mycophenolatemofetil and enoxaparin have contributed significantly toward treatment of the disease.Hence; we planned the present study to assess and compare the efficacy of topical tacrolimus ointment and triamcinolone acetonideointment in treating OLP patients. Materials & Methods: The present study included assessment of efficacy of in oral lichen planus patients. A total of 20 patients with OLP were included in the present study. All the patients were broadly divided into two study groups; group A and group B, with 10 patients in each group. Group A included patients who were treated with topical tacrolimus ointment, while group B included patients treated with triamcinolone acetonide 0.1% in hypromellose ointment. All the patients were treated with their specific treatment for a period of 2 months. All the patients were checked on follow-up after six months’ time. Results: fewer side effects and better treatment was seen in patients of group A>Conclusion: Topical tacrolimus ointment shows better results in treating OLP patients. Key words: Acetonide, Oral Lichen Planus, Tacrolimus.