Journal of AdvancedMedical and Dental Sciences Research

Background: Hyponatremia can be a life-threatening illness among hospitalized children. Present study aimed to compare the sodium and CRP level in children with lower respiratory tract Infections (LRTI), and to investigate whether there is a link between hyponatremia and the severity and outcome of LRTI. Materials and Methods: Total of 200 children between the age group of 2 months to 5 years were involved in the study which includes 100 as control and 100 of lower respiratory tract infection mainly pneumonia, bronchiolitis, wheezing, empyema. Aseptically, 3 ml of venous blood was drawn from the antecubital vein from each patient and were analysed for serum sodium level and serum CRP level. Statistical analysis of collected data has been done by using SPSS (18.0). P value < 0.05 was considered as statistically significant. Results: Statistically significant differences were observed in the mean serum sodium level of controls 136 ± 2.86 and Children with pneumonia (126 ± 4.25). (p = 0.001). Statistically significant differences were observed in the mean serum CRP level of controls (3.46 ± 1.12) and Children suffering from pneumonia (4.11 ± 2.67).  After applying Pearson’s correlation coefficient it was found that there is a negative correlation between serum sodium level and CRP in cases. Whereas, in control it do not shows any significant correlation. Conclusion: Hyponatremia has clearly been shown to be a common electrolyte abnormality in lower respiratory tract disease mainly in pneumonia. Thus the appropriate fluid therapy must be carefully arranged in children with lower respiratory tract infection.
Key words: Bronchiolitis, Hyponatremia, Pneumonia, ADH, LRTI.

Corresponding Author: Dr. Manju Tripathi, Assistant professor, Department of Pediatrics, TS Mishra Medical College and Hospital Lucknow, Uttar Pradesh, India

This article may be cited as: Tripathi M. Hyponatremia in Children with Acute Lower Respiratory Tract Infections. J Adv Med Dent Scie Res 2016;4(5):146-149.