Journal of AdvancedMedical and Dental Sciences Research

Background: In diabetic foot, ulceration occurs as a result of trauma in the presence of neuropathy and/or peripheral vascular disease with infection as a secondary phenomenon following disruption of the protective epidermis. The present study was conducted to evaluate the efficacy of PRP dressings in DFU. Materials & Methods: The present study was conducted on 82 patients of both genders (males- 46, females- 36). Wound size as per maximum length and breadth and area were recorded and three PRP dressings were given on day 0, 1st week and at 3rd week. On 2nd week, and 4th, 5th, 6th and 8th weeks only saline dressings were applied at weekly intervals. On every dressing patient’s wound was measured in maximum length and maximum breadth by using a scale and area was calculated.
Results: Age group 20-30 years had 1 male and 2 females, 30-40 years had 12 males and 10 females, 40-50 years had 13 males and 10 females and >50 years had 20 males and 14 females. The difference was significant (P< 0.05). The occurrence of ulcer was fore foot (males- 12, females- 8), mid foot (males- 26, females- 18) and hind foot (males- 8, females- 10). The difference was significant (P< 0.05). The size of ulcer decreased significantly which was 4.2 cm2 in males and 3.8cm2 in females on 0 day, 3.6 cm2 and 3.2 cm2 in females at 1st week, 2.4 cm2 and 2.6 cm2 in males and females at 3rd week and 1.2 cm2 and 0.8 cm2 in males and females respectively at 8th week. Conclusion: PRP is an effective dressing which shows better result in the management of diabetic foot ulcers. There is significant reduction in size of the ulcer with use.
Key words: Diabetic, foot, PRP, Wound.

Corresponding author: Dr. Vinod Kumar, Assistant Professor, Department of Orthopedics, NIMS Jaipur, Rajasthan, India

This article may be cited as: Kumar V. Management of Diabetic Foot Ulcer using Platelet Rich Plasma Dressings- A Clinical Study. J Adv Med Dent Scie Res 2015;3(2):191-193.