Aim: The aim of this study was to determine the incidence rate of oral Candida species in diabetic subjects. Methods: A total of 100 non-insulin dependent diabetes patients including 50 diabetic and 50 non-diabetic denture wearers visited in department of dentistry wereselected. Material for analysis included swabs taken from the palate mucosa and mucosal part of denture surfaces in denture wearers .Their oral rinse samples were collected for mycological examination, and cultured on CHROM agar Candida plates. Frequency and density of Candida species isolated from both groups were compared using SPSS software. Results: The higher density of isolated colonies was seen in diabetic group in compare with control group (P = 0.0001). C. albicans was the most common isolated Candida species in both groups, though diabetic patients with dentures had more non-albicans Candida isolated from their dentures compared to non-diabetic patients. Conclusions: Mycological findings from the present study revealed that diabetes mellitus can increase colonization of Candida in denture and mouth. By elimination of local and systemic factors in diabetic patients and improving their oral health care, Candida colonization and the risk of oral and systemic candidiasis will be decreased.
Keywords: Candida albicans, Colonization, Denture, Diabetes.