Journal of AdvancedMedical and Dental Sciences Research

Background: It is a common dermatological problem, reported more in females than in males. It is a condition which is neither health threatening nor associated with any morbidity, but it can influence an individual’s quality of life. The present study was conducted to compare the effect of topical hydroquinone and 30% salicylic acid peels on patients with POH. Materials & Methods: Patients were divided into 2 groups. Group I (30) received 4% HQ daily and group II (30) received 30% SA peel once in 2 weeks for 3 months. The peel was applied serially at 2 weekly intervals at 0, 2, 4, 6, 8, and 10 weeks after the test peel.  Subjective assessment of the response was also made by the patient and the treating physician at 4, 8, and 12 weeks and was evaluated on a visual analog scale (VAS) as 1 (worse), 2 (no change), 3 (<30%), 4 (30–60%), and 5 (>60%). Results: Group I (HQ) had 30 and group II (SA) had 30 patients. The difference was non- significant (P-1). Age group 10-20 years had 6 males and 18 females, age group 20-30 years had 10 males and 12 females and age group 30-40 years had 4 males and 10 females. The difference was significant (P< 0.05). Maximum improvement was observed at 12 weeks in both groups. There was no statistical difference in VAS score at 4, 8 and 12 weeks between both groups. Conclusion: Periocular pigmentation is frequently seen in multiple members of the same family. Possible causative factors include anemia, nutritional status, UV component, Contact dermatitis, estrogens and NSAIDS.
Key words: Hydroquinone, Periocular pigmentation, Salicylic acid.

Corresponding author: Dr. Bhawna Kapoor, Senior Resident, Department of  Dermatology Mayo Institute of Medical Sciences Gadia, Barabanki, UP, India

This article may be cited as: Kapoor A, Kapoor B. A Comparative Analysis of use of Hydroquinone and Salicylic Acid in patients with Peri- Orbital Hyperpigmentation. J Adv Med Dent Scie Res 2015;3(2):178-180.