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Volume 5 Issue 4 (April, 2017)

Original Articles

Assessment of Cases of Dengue Fever in Study Population- A Clinical Study
Vipin Goel, Virendra Kumar

Background: Dengue viruses are mosquito-borne flavi viruses that plagued people for centuries. Dengue fever (DF) and its more severe form i.e. dengue hemorrhagic fever (DHF), are caused by any one of the four serotypes of dengue virus belonging to the genus flavivirus transmitted by Aedes aegyptei. The present study was conducted to assess the cases of dengue in study population. Materials & Methods: This study was conducted in the department of general medicine in year 2015. It included 450 patients of both gender. After taking the history, clinical examination and laboratory investigation like complete hemogram, urea, creatinine, liver function test, chest, X-ray, ECG and ultra sound of abdomen was taken. Platelet counts were estimated. The diagnosis of pleural effusion was confirmed by X-chest. In ECG finding tachycardia was present in all the patients of shock and haemorrhage. All were subjected to serology NS1, IgM, IgG/IgM with rapid kit test. Results: Out of 450 patients, males were 220 and females were 230. The difference was non- significant (P-1). Age group 21-30 years consisted of 180 patients, age group 31-40 years had 135 patients, age group 41-50 years had 77 patients and >50 years had 58 patients. The difference was significant (P- 0.04). Common clinical manifestations in patients were fever (410), headache (250), myalgia (205), rash (157), bleeding (42), GIT manifestations (386) and shock (12). The difference was significant (P- 0.05). Platelets counts were <10000/cmm in 50 patients, <250000/cmm in 135 patients, <75000/cmm in 210 patients and 75000-150000/cmm in 55 patients. The difference was significant (P- 0.05). Serological test showed NS1 in 140 patients, IgM in 178 patients and IgG in 132 patients. Most of cases were seen in winters, September (125), October (210), November (70), December (35), January (5), February, may and july (1) each and September (2). The difference was significant (P- 0.05). Conclusion: Dengue is a viral fever caused by biting of mosquito. Proper care should be taken to avoid accumulation of water to prevent spread of mosquitoes. Bleeding, fever and decrease in platelets counts should be dealt seriously.
Key words: Aedes aegyptei, Dengue fever, flavi viruses.

 
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