One of the most common malignant tumours of oral cavity is Oral squamous cell carcinoma (OSCC). The aetiology of epithelial cancer of the head and neck is considered to be a multifactorial, sequential process. DNA viruses are found in many different cancers and are also capable of transforming cells to a malignant phenotype. Human Papilloma Virus (HPV) has been proposed as risk factors in OSCC development and HPV type 16 is the most important subtype. Hence, in the present review, we aim to highlight the association of viruses in causation of oral cancer.
Key words: Oral Cancer, Review, Viruses.