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Volume 5 Issue 9 (September, 2017)

Original Articles

Effect of Intrathecal Hyperbaric Bupivacaine with Midazolam and Hyperbaric Bupivacaine alone in Lower Limb Orthopaedic Surgeries
V N Vaid, Shipra Singh, Pankaj Mishra, K G Rao

Background:
Spinal anesthesia is successful in the administration of perioperative pain which stretches out into the underlying post operative period. With a specific end goal to boost postoperative agony free period various methods and more up to date medicates have been attempted. In this examination, the anaesthetic  properties of 0.5% hyperbaric bupivacaine with 0.4 ml of ordinary saline and 0.5% hyperbaric bupivacaine with 2 mg of midazolam given intrathecally were compared. Materials and Methods: Patients of either sexual orientation (men = 44, ladies = 16), aged between 25-60 years, were haphazardly allotted to two gatherings (30 each). Group 1 got 0.5% hyperbaric bupivacaine with saline intrathecally, and Group 2 got 0.5% hyperbaric bupivacaine with additive free midazolam 2 mg intrathecally. Peak sensory level, total duration of analgesia, duration of motor blockade, pain score using the Visual Analogue Scale, along with vital parameters, namely heart rate and systolic, diastolic and mean blood pressure were assessed. Results: The duration of analgesia watched was altogether higher in Group 2 (321 ± 25.5 minutes) versus Group 1 (157 ± 17.4 minutes), and the pain score was less in Group 2 when contrasted with Group 1. The time of onset of sensory and motor block was essentially longer in group 2. Hemodynamic changes did not vary in patient of either gathering. The side effects were negligible in both the gatherings. Conclusion: Intrathecal administration midazolam in blend with hyperbaric bupivacaine 0.5% delivers better quality of analgesia, longer span of absense of pain, with mellow sedation and negligible symptoms along these lines lessening post operative pain relieving prerequisite.
Key Words: Hyperbaric bupivacaine, intrathecal midazolam, spinal anesthesia, postoperative analgesia.
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