Journal of AdvancedMedical and Dental Sciences Research

Background: Dengue is the most common viral disease in humans.  Every year about 50 - 100 million individuals are infected. Dengue is reported in both urban and rural area. The present study was conducted to assess the cases of dengue fever by clinical and laboratories findings. Materials & Methods: This study was conducted in the department of General medicine in year 2015. It included 1025 patients who diagnosed with dengue fever. All were informed regarding the study and consent was taken. Ethical clearance was obtained from institutional committee. Detailed history and careful clinical examination was performed on each patient. Laboratory investigations included were hemoglobin (Hb), DLC, TLC, platelet count, hematocrit, liver function tests (LFT), blood urea and serum creatinine. All were also subjected to chest radiograph and ultrasound scan of abdomen. Results: Out of 1025 patients, males were 625 and females were 600. The difference was non- significant (P- 1). Age group 10- 20 years had 105 males and 100 females, age group 20-30 years had 180 males and 170 females, age group 30-40 years had 210 males and 190 females and above 40 years consisted of 130 males and 140 females. The difference was non- significant (P- 1). Common symptoms in patients were fever (1025), headache (990), myalgia (923), retro- orbital pain (152). Other symptoms were nausea/ vomiting (25), diarrhea (12), skin rashes (359) and bradycardia (18), bleeding (24), ascites (72), hepatomegaly (57) and splenomegaly (62). Laboratories findings were thrombocytopenia (< 50,000/ cumm) (680), leucopenia (< 4,000/ cu mm) (218), raised AST and ALT (> 45 IU/L) (854), and raised hematocrit (> 45%) (248). Conclusion: Dengue fever presents clinical and laboratories findings which helps in early detection. Fever is the main symptom and vomiting, hepatomegaly and splenomegaly etc. are associated symptoms. AST and ALT are important reliable laboratories findings which help in early diagnosis of cases as these parameters are highly raised in patients.
Key words: Dengue, fever, nausea/ vomiting.